The goal of this webinar is to demonstrate the clinical utility and discovery potential of genome-wide methylation profiling coupled with a novel machine learning-based algorithm for the diagnosis of various congenital disorders.

Presented by: 

NSGC Genomic Technologies SIG
1. Linda Hasadsri, MS, MD, PhD
2. Adriana Malheiro, MS, LCGC 

Date: December 9, 2025  

Learning Objectives: 

1. Compare current methodologies utilized for detection of differential methylation.
2. Describe the advantages and disadvantages of performing genome-wide methylation profiling in diagnostic odyssey cases.
3. Describe strategies to search for tests in GTR using the new search interface.
4. Explain how to use the new GTR tools to compare tests and download test descriptions for analysis. 

Continuing Education Unit Approval:

The National Society of Genetic Counselors (NSGC) has authorized National Society of Genetic Counselors (NSGC) to offer up to 1 Category 1 contact hours for Whole Methylome for Congenital Disorders and an Update on the NIH Genetic Testing Registry (GTR®). The American Board of Genetic Counseling (ABGC) will accept CEUs earned at this program for the purposes of genetic counselor certification and recertification. 

Successful Completion:

1. View recording
2. Pass quiz
3. Complete evaluation